CD39 anticorps

N° du produit ABIN7113721

Cet anticorps Lapin Polyclonal détecte spécifiquement CD39 dans WB, FACS, IHC, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CD39 anticorps (ABIN7113721)

Antigène: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD39 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-CD39 anticorps

Fonction: ENTPD1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ectonucleoside triphosphate diphosphohydrolase 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CD39

Antigène: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Autre désignation: ENTPD1

Sujet:

Synonyms: Ectonucleoside triphosphate diphosphohydrolase 1|ATP diphosphohydrolase (ATP-DPH, ATPDase)|Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1, Ecto-ATPase 1)|Ecto-apyrase|Lymphoid cell activation antigen|Nucleoside triphosphate diphosphohydrolase 1 (NTPDase1)|ENTPD1|CD39

Background: ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785).And it is a 70-to 100- kDa protein that is heavily N-glycosylated(PMID:7930580). It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms.(PMID: 12694193). The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39(38-478aa) molecule.

Poids moléculaire: 75-95 kDa

UniProt: P49961